The global rise in obesity rates necessitates effective treatment strategies. Among pharmaceutical options, orlistat stands out. Orlistat inhibits fat absorption in the gut. It helps reduce weight by blocking dietary fat digestion. Unlike other weight loss drugs, it has a distinct mechanism. This sets it apart in the realm of obesity management.
Orlistat: Mechanism and Efficacy
Orlistat acts in the gastrointestinal tract. It prevents lipase enzymes from breaking down dietary fats. This leads to decreased calorie absorption. Clinical trials validate its efficacy. Participants show significant weight loss. These trials include diverse populations. Results consistently favor orlistat over placebo. Most studies report a 5-10% body weight reduction. Orlistat demonstrates robust performance in long-term use.
Despite its effectiveness, orlistat has limitations. It can cause gastrointestinal side effects. These include oily stools and flatulence. Such